Today science uses the biological term “mutation” despite it often is describing two wildly different– if not opposite events: (1) Changes at reproduction as a function of heredity as performed by preexisting DNA function of alleles (“germline mutation”) and (2) genetic errors outside intended hereditary function (we shall call “metabolic mutation”). Metabolic mutations are always bad, in fact they account for 2/3 of all cancers in humans.1
New cells are formed when an existing cell divides and copies its DNA, one cell turning into two. Every time DNA is copied, about three random (“metabolic”) mutations occur” Vogelstein said.https://hub.jhu.edu/2017/03/23/cancer-mutations-caused-by-random-dna-mistakes/
We all harbor these kinds of (“metabolic”) mutations (errors due to DNA replication) and most don’t hurt us because the body’s defense mechanisms spot and fix the damage”Dr. Otis Brawley of the American Cancer Society
However, sometimes the errors hit the wrong spot and damage genes that can spur cancerous growths or damage the very genes which are used by DNA to spot and fix problems. Then, when these damaged cells are replicated, important mutations gradually build up over time. That’s one reason the risk of cancer increases with age.1
Mutation “Type 1”: (“Germline” mutations)
This hereditary type we are coining as a “germline function” are really not mutations at all. Germline affects involves hereditary diversity at reproduction. Germline function is the only “mutation” which can be pass new genetics to offspring. In other words, this is the only place where “evolution” could occur. However, these causes are expressly not “errors” at all.
We find germline function provides hereditary modifications that are allowed, caused, and limited by DNA (allele) function which occur only at reproduction. It is this DNA’s function that is used as the mechanism which causes diversity of offspring only within the same species.2
Mutation “Type 2” we shall coin as “Metabolic Mutations”
By contrast metabolic mutations are literally ‘errors’ which occur randomly, spontaneously, or due to harmful environmental conditions during DNA replication within the cell during metabolism–not reproduction. Environmental conditions such as smoking or exposure to the sun are examples that may cause damage ultimately at the DNA level.
Metabolic mutations are detrimental to all living organisms. The vast majority of these mutational errors do not all pass to the germline function (although few do) they therefore fail as a mechanism for the Origin of Species Evolution.
Most cancers are caused by metabolic mutations.
John Hopkins University has identified that metabolic mutational errors cause cancer. Cristian Tomasetti, assistant professor of biostatistics stated that these (metabolic mutational) copying mistakes are a “potent source of cancer mutations” and “2/3 of all cancers in humans are caused by these mistakes.”1
So, why are these two functions called the same word?
To consider the beneficial DNA hereditary function at reproduction (what we called “Germline function”) vs. the detrimental mutational error of metabolic mutation, to use the same word to define both functions is absurd.
Scientists continue this despite fully knowing that heredity function of DNA alleles is preexisting and not due to spontaneous, random, errors. All while science knows that metabolic mutations are actually errors which are detrimental, destructive, and in many cases deadly.1 These clearly are two completely different phenomena within the field of biology, yet they share the same name.
Natural Selection and Mutation “bait and switch”.
Lastly, while modern biology distracts us by calling both functions of DNA mutation, despite the obvious and factually distinctly differing functions of these so-called mutations, here is where the bait and switch happens! Evolution appeals to the obvious and positive effects of DNA alleles at reproduction and proclaims that these ‘mutations’ (mixing in both types for good measure) are Darwin’s Natural Selection, both observable and clearly a scientific fact! Which may be true for ‘germline mutations’ (DNA at reproduction), which we agree offspring are indeed diversified at reproduction within their same species: such affects are both good and observable. We might even agree that this does seem to “add up those things which are good” in any given species of life.
However, we must point out, that metabolic mutation (which occurs outside of reproduction) fails to move (evolve) anything forward. These metabolic mutations fail to “reject that which is bad” because they are in fact themselves what is “bad”. They conclude as cancers, sickness, disease, and death.1
Additionally, DNA, as it replicates, is constantly working NOT to “evolve” in the sense that it avoids mistakes using sophisticated self-monitoring, self-editing, self-correcting, and self-replicating processes and enzymatic mechanisms. DNA works to always make identical copies of itself without any mutational errors.3 However, these mutational errors do accumulate over the generations (called “genetic entropy”). This is observable and we find each generation gains thousands of mutations more than the prior generation.4
The downward spiral becomes unstoppable, because every member of the population has the same problem: natural selection can’t choose between ‘fit’ and ‘less fit’ individuals if every member of the population is, more or less, equally mutated. The population descends into sickness and finally becomes extinct. There’s simply no way to stop it.”https://creation.com/genetic-entropy-and-simple-organisms
DNA function drives diversity and (by function) obstructs evolution. DNA can be considered an analogy for an informational blueprint (instructions), written in code like computer programming, used by the cell to assemble every component of all living organisms on earth.
We find “Natural Selection” (variety within the same species) limited by the preexisting DNA (allele) function at reproduction or as heredity. We find errors due to mutations outside of DNA function (what we coined as Type 2 mutations) as a true mutation “error”. We also found that these mutations cannot be passed to offspring 2 and are mostly detrimental to life.1 Such metabolic mutations fail therefore to “reject that which is bad” because they are not hereditary. Such a failure can be clearly expressed when a person dies of cancer.
We find factually, that DNA function (so called germline mutations) work to maintain and generate variety and diversity within the same species, all while constantly limiting, correcting, and trying to stop all mutational errors.3 Therefore, in conclusion, we find germline function as an explanation for “Natural Selection” but this is where it ends.
To reach beyond these observable facts is to complete a “bait and switch”.
Denying that variety and diversity within populations are functions of DNA and not of “errors”. We find scientific data has largely disproved such concepts and conjecture regarding evolution beyond DNA function at reproduction within the same species.
4 “Genetic entropy and simple organisms, If genetic entropy is true, why do bacteria still exist?” by Robert Carter; October 2012 https://creation.com/genetic-entropy-and-simple-organisms